RESTASIS vs TACROLIMUS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. RESTASIS and TACROLIMUS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	RESTASIS	TACROLIMUS
Rating	72/100	New
Pharmacy pays	~$52.85 /30	$0.65 /g
Type	RX	RX
Active ingredient	CYCLOSPORINE	TACROLIMUS
Manufacturer	Allergan	Dr Reddys
Dosage forms	Emulsion	Capsule, Capsule, extended release, Injectable, Topical
Drug class	Calcineurin Inhibitor Immunosuppressant	Calcineurin Inhibitor Immunosuppressant
Boxed warning	None	Boxed warning
Half-life	about 8.4 hours (range 5 to 18 hours)	—
Treats	Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus	Atopic Dermatitis, Graft Vs Host Disease

restasis tacrolimus

Rating

72/100

New

Pharmacy pays

~$52.85 /30

$0.65 /g

Type

Active ingredient

CYCLOSPORINE

TACROLIMUS

Manufacturer

Allergan

Dr Reddys

Dosage forms

Emulsion

Capsule, Capsule, extended release, Injectable, Topical

Drug class

Calcineurin Inhibitor Immunosuppressant

Boxed warning

None

Boxed warning

Half-life

about 8.4 hours (range 5 to 18 hours)

—

Treats

Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus

Atopic Dermatitis, Graft Vs Host Disease

Frequently asked questions

What is the difference between Restasis and Tacrolimus?

Restasis contains Cyclosporine, while Tacrolimus contains Tacrolimus — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.