RENAGEL vs SEVELAMER CARBONATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. RENAGEL and SEVELAMER CARBONATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	RENAGEL	SEVELAMER CARBONATE
Rating	70/100	70/100
Pharmacy pays	~$32.31 /30	~$6.60 /30
Type	RX	RX
Active ingredient	SEVELAMER HYDROCHLORIDE	SEVELAMER CARBONATE
Manufacturer	Genzyme	Bionpharma
Dosage forms	Tablet, Capsule	Powder, Tablet
Drug class	—	Phosphate Binder
Boxed warning	None	None
Treats	Hyperphosphatemia	Hyperphosphatemia

renagel sevelamer carbonate

Rating

70/100

Pharmacy pays

~$32.31 /30

~$6.60 /30

Type

Active ingredient

SEVELAMER HYDROCHLORIDE

SEVELAMER CARBONATE

Manufacturer

Genzyme

Bionpharma

Dosage forms

Tablet, Capsule

Powder, Tablet

Drug class

—

Phosphate Binder

Boxed warning

None

Treats

Hyperphosphatemia

Frequently asked questions

Which is better-rated, Renagel or Sevelamer Carbonate?

Renagel and Sevelamer Carbonate are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Renagel or Sevelamer Carbonate?

Sevelamer Carbonate costs pharmacies less to acquire — about $6.60 vs $32.31 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Renagel and Sevelamer Carbonate?

Renagel contains Sevelamer Hydrochloride, while Sevelamer Carbonate contains Sevelamer Carbonate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.