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RELISTOR vs REZENOPY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. RELISTOR and REZENOPY are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
New

Pharmacy pays

$4.41 /mL

Type

RX
RX

Active ingredient

METHYLNALTREXONE BROMIDE
NALOXONE HYDROCHLORIDE

Manufacturer

Dosage forms

Injectable, Tablet
Spray/Inhaler

Drug class

Opioid Antagonist
Opioid Antagonist

Boxed warning

None
None

Half-life

30 to 81 minutes (mean 64 ± 12 minutes)

Treats

Constipation
Opioid-Related Disorders, Respiration Disorders, Septic Shock

Frequently asked questions

What is the difference between Relistor and Rezenopy?

Relistor contains Methylnaltrexone Bromide, while Rezenopy contains Naloxone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.