RALDESY vs SERTRALINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. RALDESY and SERTRALINE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	RALDESY	SERTRALINE HYDROCHLORIDE
Rating	New	70/100
Pharmacy pays	~$1.52 /30	~$1.09 /30
Type	RX	RX
Active ingredient	TRAZODONE HYDROCHLORIDE	SERTRALINE HYDROCHLORIDE
Manufacturer	Kamat	Ascent Pharms Inc
Dosage forms	Solution	Solution, Tablet
Drug class	Serotonin Reuptake Inhibitor	Serotonin Reuptake Inhibitor
Boxed warning	Boxed warning	Boxed warning
Half-life	about 7 hours (roughly 5 to 9 hours for the slower elimination phase)	about 26 hours
Treats	Depressive Disorder, Sleep Initiation and Maintenance Disorders	Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder

raldesy sertraline hydrochloride

Rating

New

70/100

Pharmacy pays

~$1.52 /30

~$1.09 /30

Type

Active ingredient

TRAZODONE HYDROCHLORIDE

SERTRALINE HYDROCHLORIDE

Manufacturer

Kamat

Ascent Pharms Inc

Dosage forms

Solution

Solution, Tablet

Drug class

Serotonin Reuptake Inhibitor

Boxed warning

Half-life

about 7 hours (roughly 5 to 9 hours for the slower elimination phase)

about 26 hours

Treats

Depressive Disorder, Sleep Initiation and Maintenance Disorders

Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder

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Frequently asked questions

Which is cheaper, Raldesy or Sertraline Hydrochloride?

Sertraline Hydrochloride costs pharmacies less to acquire — about $1.09 vs $1.52 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Raldesy and Sertraline Hydrochloride?

Raldesy contains Trazodone Hydrochloride, while Sertraline Hydrochloride contains Sertraline Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.