PROPYLTHIOURACIL vs TAPAZOLE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. PROPYLTHIOURACIL and TAPAZOLE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PROPYLTHIOURACIL	TAPAZOLE
Rating	New	New
Pharmacy pays	~$8.42 /30	~$2.28 /30
Type	RX	RX
Active ingredient	PROPYLTHIOURACIL	METHIMAZOLE
Manufacturer	Halsey	King Pharms LLC
Dosage forms	Tablet	Tablet
Drug class	Thyroid Hormone Synthesis Inhibitor	Thyroid Hormone Synthesis Inhibitor
Boxed warning	None	None
Treats	Goiter, Thyroid Crisis	Goiter, Thyroid Crisis

propylthiouracil tapazole

Rating

New

Pharmacy pays

~$8.42 /30

~$2.28 /30

Type

Active ingredient

PROPYLTHIOURACIL

METHIMAZOLE

Manufacturer

Halsey

King Pharms LLC

Dosage forms

Tablet

Drug class

Thyroid Hormone Synthesis Inhibitor

Boxed warning

None

Treats

Goiter, Thyroid Crisis

Frequently asked questions

Which is cheaper, Propylthiouracil or Tapazole?

Tapazole costs pharmacies less to acquire — about $2.28 vs $8.42 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Propylthiouracil and Tapazole?

Propylthiouracil contains Propylthiouracil, while Tapazole contains Methimazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.