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PROPAFENONE HYDROCHLORIDE vs TAMBOCOR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. PROPAFENONE HYDROCHLORIDE and TAMBOCOR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

propafenone hydrochloridetambocor

Rating

72/100
70/100

Pharmacy pays

~$10.51 /30
~$5.39 /30

Type

RX
RX

Active ingredient

PROPAFENONE HYDROCHLORIDE
FLECAINIDE ACETATE

Manufacturer

Rising
Alvogen

Dosage forms

Capsule, extended release, Tablet
Tablet

Drug class

Antiarrhythmic
Antiarrhythmic

Boxed warning

Boxed warning
None

Half-life

about 2 to 10 hours (immediate-release) in the ~90% of adults who are extensive CYP2D6 metabolizers
—

Treats

Atrial Fibrillation, Supraventricular Tachycardia
Atrial Fibrillation, Supraventricular Tachycardia, Ventricular Tachycardia

Frequently asked questions

Which is better-rated, Propafenone Hydrochloride or Tambocor?

By our independent rating, Propafenone Hydrochloride scores higher — 3.6 vs 3.5 out of 5 for Tambocor. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Propafenone Hydrochloride or Tambocor?

Tambocor costs pharmacies less to acquire — about $5.39 vs $10.51 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Propafenone Hydrochloride and Tambocor?

Propafenone Hydrochloride contains Propafenone Hydrochloride, while Tambocor contains Flecainide Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.