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PROMETHAZINE PLAIN vs PROMETHEGAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Rating

New
70/100

Pharmacy pays

~$1.53 /30
~$1.53 /30

Type

RX
RX

Active ingredient

PROMETHAZINE HYDROCHLORIDE
PROMETHAZINE HYDROCHLORIDE

Dosage forms

Syrup
Suppository

Drug class

Phenothiazine
Phenothiazine

Half-life

about 9 to 16 hours
about 9 to 16 hours

Treats

Anaphylaxis, Allergic Conjunctivitis, Motion Sickness
Anaphylaxis, Allergic Conjunctivitis, Motion Sickness

Frequently asked questions

Which is cheaper, Promethazine Plain or Promethegan?

Pharmacies pay about the same to acquire either one — roughly $1.53 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Promethazine Plain and Promethegan?

Both Promethazine Plain and Promethegan share the active ingredient Promethazine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.