PROLENSA vs VOLTAREN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. PROLENSA and VOLTAREN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PROLENSA	VOLTAREN
Rating	New	70/100
Pharmacy pays	$14.72 /mL	$0.36 /mL
Type	RX	RX
Active ingredient	BROMFENAC SODIUM	DICLOFENAC SODIUM
Manufacturer	Bausch and Lomb	Novartis
Dosage forms	Drops	Tablet, delayed release
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	None
Half-life	—	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)
Treats	Inflammation, Postoperative Pain, Eye Pain	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

prolensa voltaren

Rating

New

70/100

Pharmacy pays

$14.72 /mL

$0.36 /mL

Type

Active ingredient

BROMFENAC SODIUM

DICLOFENAC SODIUM

Manufacturer

Bausch and Lomb

Novartis

Dosage forms

Drops

Tablet, delayed release

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

—

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

Treats

Inflammation, Postoperative Pain, Eye Pain

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Frequently asked questions

Which is cheaper, Prolensa or Voltaren?

Voltaren costs pharmacies less to acquire — about $0.36 vs $14.72 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Prolensa and Voltaren?

Prolensa contains Bromfenac Sodium, while Voltaren contains Diclofenac Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.