PROCHLORPERAZINE EDISYLATE vs PROMETHAZINE PLAIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. PROCHLORPERAZINE EDISYLATE and PROMETHAZINE PLAIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PROCHLORPERAZINE EDISYLATE	PROMETHAZINE PLAIN
Rating	New	New
Pharmacy pays	—	~$1.53 /30
Type	RX	RX
Active ingredient	PROCHLORPERAZINE EDISYLATE	PROMETHAZINE HYDROCHLORIDE
Manufacturer	Caplin	Pharmobedient
Dosage forms	Injectable	Syrup
Drug class	Phenothiazine	Phenothiazine
Boxed warning	Boxed warning	Boxed warning
Half-life	—	about 9 to 16 hours
Treats	Anxiety Disorders, Dementia, Nausea	Anaphylaxis, Allergic Conjunctivitis, Motion Sickness

prochlorperazine edisylate promethazine plain

Rating

New

Pharmacy pays

—

~$1.53 /30

Type

Active ingredient

PROCHLORPERAZINE EDISYLATE

PROMETHAZINE HYDROCHLORIDE

Manufacturer

Caplin

Pharmobedient

Dosage forms

Injectable

Syrup

Drug class

Phenothiazine

Boxed warning

Half-life

—

about 9 to 16 hours

Treats

Anxiety Disorders, Dementia, Nausea

Anaphylaxis, Allergic Conjunctivitis, Motion Sickness

Frequently asked questions

What is the difference between Prochlorperazine Edisylate and Promethazine Plain?

Prochlorperazine Edisylate contains Prochlorperazine Edisylate, while Promethazine Plain contains Promethazine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.