PRIMIDONE vs VALPROIC ACID

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. PRIMIDONE and VALPROIC ACID are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PRIMIDONE	VALPROIC ACID
Rating	70/100	New
Pharmacy pays	~$2.89 /30	~$1.02 /30
Type	RX	RX
Active ingredient	PRIMIDONE	VALPROIC ACID
Manufacturer	Amneal	Chartwell Rx
Dosage forms	Tablet	Solution
Drug class	Anti-Epileptic Agent	Anti-Epileptic Agent
Boxed warning	None	None
Treats	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor	Alzheimer Disease, Bipolar Disorder, Epilepsy

primidone valproic acid

Rating

70/100

New

Pharmacy pays

~$2.89 /30

~$1.02 /30

Type

Active ingredient

PRIMIDONE

VALPROIC ACID

Manufacturer

Amneal

Chartwell Rx

Dosage forms

Tablet

Solution

Drug class

Anti-Epileptic Agent

Boxed warning

None

Treats

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

Alzheimer Disease, Bipolar Disorder, Epilepsy

Frequently asked questions

Which is cheaper, Primidone or Valproic Acid?

Valproic Acid costs pharmacies less to acquire — about $1.02 vs $2.89 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Primidone and Valproic Acid?

Primidone contains Primidone, while Valproic Acid contains Valproic Acid — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.