PREZISTA vs REYATAZ

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. PREZISTA and REYATAZ are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PREZISTA	REYATAZ
Rating	New	72/100
Pharmacy pays	~$49.71 /30	~$52.63 /30
Type	RX	RX
Active ingredient	DARUNAVIR	ATAZANAVIR SULFATE
Manufacturer	Janssen Prods	Bristol Myers Squibb
Dosage forms	Suspension, Tablet	Capsule, Powder
Drug class	Protease Inhibitor	Protease Inhibitor
Boxed warning	None	None
Treats	Acquired Immunodeficiency Syndrome, Hiv Infections	Acquired Immunodeficiency Syndrome

prezista reyataz

Rating

New

72/100

Pharmacy pays

~$49.71 /30

~$52.63 /30

Type

Active ingredient

DARUNAVIR

ATAZANAVIR SULFATE

Manufacturer

Janssen Prods

Bristol Myers Squibb

Dosage forms

Suspension, Tablet

Capsule, Powder

Drug class

Protease Inhibitor

Boxed warning

None

Treats

Acquired Immunodeficiency Syndrome, Hiv Infections

Acquired Immunodeficiency Syndrome

Frequently asked questions

Which is cheaper, Prezista or Reyataz?

Prezista costs pharmacies less to acquire — about $49.71 vs $52.63 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Prezista and Reyataz?

Prezista contains Darunavir, while Reyataz contains Atazanavir Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.