PRED FORTE vs ZYFLO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. PRED FORTE and ZYFLO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PRED FORTE	ZYFLO
Rating	72/100	70/100
Pharmacy pays	$0.60 /mL	~$61.45 /30
Type	RX	RX
Active ingredient	PREDNISOLONE ACETATE	ZILEUTON
Manufacturer	Abbvie	Chiesi
Dosage forms	Drops	Tablet
Drug class	Corticosteroid	5-Lipoxygenase Inhibitor
Boxed warning	None	None
Half-life	2 to 4 hours	—
Treats	Adrenal Insufficiency, Hemolytic Anemia, Asthma	Asthma

pred forte zyflo

Rating

72/100

70/100

Pharmacy pays

$0.60 /mL

~$61.45 /30

Type

Active ingredient

PREDNISOLONE ACETATE

ZILEUTON

Manufacturer

Abbvie

Chiesi

Dosage forms

Drops

Tablet

Drug class

Corticosteroid

5-Lipoxygenase Inhibitor

Boxed warning

None

Half-life

2 to 4 hours

—

Treats

Adrenal Insufficiency, Hemolytic Anemia, Asthma

Asthma

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Frequently asked questions

Which is better-rated, Pred Forte or Zyflo?

By our independent rating, Pred Forte scores higher — 3.6 vs 3.5 out of 5 for Zyflo. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Pred Forte and Zyflo?

Pred Forte contains Prednisolone Acetate, while Zyflo contains Zileuton — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.