PRADAXA vs XARELTO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. PRADAXA and XARELTO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PRADAXA	XARELTO
Rating	72/100	72/100
Pharmacy pays	~$26.96 /30	$0.96 /mL
Type	RX	RX
Active ingredient	DABIGATRAN ETEXILATE MESYLATE	RIVAROXABAN
Manufacturer	Boehringer Ingelheim	Janssen Pharms
Dosage forms	Capsule, Oral pellets	Powder, Tablet, Kit
Drug class	Direct Thrombin Inhibitor	Factor Xa Inhibitor
Boxed warning	Boxed warning	Boxed warning
Half-life	—	about 5 to 9 hours (11 to 13 hours in older adults)
Treats	Pulmonary Embolism, Venous Thrombosis	Pulmonary Embolism, Venous Thrombosis

pradaxa xarelto

Rating

72/100

Pharmacy pays

~$26.96 /30

$0.96 /mL

Type

Active ingredient

DABIGATRAN ETEXILATE MESYLATE

RIVAROXABAN

Manufacturer

Boehringer Ingelheim

Janssen Pharms

Dosage forms

Capsule, Oral pellets

Powder, Tablet, Kit

Drug class

Direct Thrombin Inhibitor

Factor Xa Inhibitor

Boxed warning

Half-life

—

about 5 to 9 hours (11 to 13 hours in older adults)

Treats

Pulmonary Embolism, Venous Thrombosis

Frequently asked questions

Which is better-rated, Pradaxa or Xarelto?

Pradaxa and Xarelto are tied at 3.6 out of 5 by our independent rating.

What is the difference between Pradaxa and Xarelto?

Pradaxa contains Dabigatran Etexilate Mesylate, while Xarelto contains Rivaroxaban — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.