POSIMIR vs XARACOLL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. POSIMIR and XARACOLL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	POSIMIR	XARACOLL
Rating	New	New
Pharmacy pays	$0.06 /mL	$0.06 /mL
Type	RX	RX
Active ingredient	BUPIVACAINE	BUPIVACAINE HYDROCHLORIDE
Manufacturer	Innocoll	Innocoll
Dosage forms	Solution	Implant
Drug class	Amide Local Anesthetic	Amide Local Anesthetic
Boxed warning	None	None
Treats	Postoperative Pain	Postoperative Pain

posimir xaracoll

Rating

New

Pharmacy pays

$0.06 /mL

Type

Active ingredient

BUPIVACAINE

BUPIVACAINE HYDROCHLORIDE

Manufacturer

Innocoll

Dosage forms

Solution

Implant

Drug class

Amide Local Anesthetic

Boxed warning

None

Treats

Postoperative Pain

Frequently asked questions

Which is cheaper, Posimir or Xaracoll?

Pharmacies pay about the same to acquire either one — roughly $0.06 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Posimir and Xaracoll?

Posimir contains Bupivacaine, while Xaracoll contains Bupivacaine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.