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POLYCILLIN vs PRINCIPEN '500'

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

Type

RX
RX

Active ingredient

AMPICILLIN/AMPICILLIN TRIHYDRATE
AMPICILLIN/AMPICILLIN TRIHYDRATE

Manufacturer

Dosage forms

Capsule

Drug class

Boxed warning

None
None

Frequently asked questions

What is the difference between Polycillin and Principen '500'?

Both Polycillin and Principen '500' share the active ingredient Ampicillin/Ampicillin Trihydrate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.