HYDROXYCHLOROQUINE SULFATE vs PLAQUENIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	HYDROXYCHLOROQUINE SULFATE	PLAQUENIL
Rating	New	New
Pharmacy pays	~$4.86 /30	~$4.86 /30
Type	RX	RX
Active ingredient	HYDROXYCHLOROQUINE SULFATE	HYDROXYCHLOROQUINE SULFATE
Manufacturer	Alkaloida Zrt	Advanz Pharma
Dosage forms	Tablet	Tablet
Drug class	Antimalarial	Antimalarial
Boxed warning	None	None
Half-life	about 40 to 50 days (terminal elimination half-life in whole blood)	about 40 to 50 days (terminal elimination half-life in whole blood)
Treats	Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria	Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria

hydroxychloroquine sulfate plaquenil

Rating

New

Pharmacy pays

~$4.86 /30

Type

Active ingredient

HYDROXYCHLOROQUINE SULFATE

Manufacturer

Alkaloida Zrt

Advanz Pharma

Dosage forms

Tablet

Drug class

Antimalarial

Boxed warning

None

Half-life

about 40 to 50 days (terminal elimination half-life in whole blood)

Treats

Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria

Frequently asked questions

Which is cheaper, Hydroxychloroquine Sulfate or Plaquenil?

Pharmacies pay about the same to acquire either one — roughly $4.86 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Hydroxychloroquine Sulfate and Plaquenil?

Both Hydroxychloroquine Sulfate and Plaquenil share the active ingredient Hydroxychloroquine Sulfate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.