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PLAN B vs SKYLA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

~$192.31 /30
~$192.31 /30

Type

RX
RX

Active ingredient

LEVONORGESTREL
LEVONORGESTREL

Dosage forms

Tablet
IUD

Drug class

Progestin
Progestin

Boxed warning

None
None

Half-life

about 36 hours (36 ± 13 hours at steady state)
about 36 hours (36 ± 13 hours at steady state)

Frequently asked questions

Which is cheaper, Plan B or Skyla?

Pharmacies pay about the same to acquire either one — roughly $192.31 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Plan B and Skyla?

Both Plan B and Skyla share the active ingredient Levonorgestrel.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.