PLAN B ONE-STEP vs PROVERA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Attribute	PLAN B ONE-STEP	PROVERA
Rating	New	60/100
Pharmacy pays	~$192.10 /30	~$553.74 /30
Type	OTC	RX
Active ingredient	LEVONORGESTREL	MEDROXYPROGESTERONE ACETATE
Manufacturer	Fdn Consumer	Pfizer
Dosage forms	Tablet	Tablet
Drug class	Progestin	Progestin
Boxed warning	None	Boxed warning
Half-life	about 36 hours (36 ± 13 hours at steady state)	—
Treats	—	Amenorrhea, Breast Neoplasms, Renal Cell Carcinoma

plan b one-step provera

Rating

New

60/100

Pharmacy pays

~$192.10 /30

~$553.74 /30

Type

OTC

Active ingredient

LEVONORGESTREL

MEDROXYPROGESTERONE ACETATE

Manufacturer

Fdn Consumer

Pfizer

Dosage forms

Tablet

Drug class

Progestin

Boxed warning

None

Boxed warning

Half-life

about 36 hours (36 ± 13 hours at steady state)

—

Treats

—

Amenorrhea, Breast Neoplasms, Renal Cell Carcinoma

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Frequently asked questions

Which is cheaper, Plan B One-Step or Provera?

Plan B One-Step costs pharmacies less to acquire — about $192.10 vs $553.74 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Plan B One-Step and Provera?

Plan B One-Step contains Levonorgestrel, while Provera contains Medroxyprogesterone Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.