PIROXICAM vs ZIPSOR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. PIROXICAM and ZIPSOR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PIROXICAM	ZIPSOR
Rating	72/100	New
Pharmacy pays	~$5.35 /30	$0.36 /mL
Type	RX	RX
Active ingredient	PIROXICAM	DICLOFENAC POTASSIUM
Manufacturer	Unichem	Assertio Speclty
Dosage forms	Capsule	Capsule
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	Boxed warning
Half-life	—	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)
Treats	Rheumatoid Arthritis, Inflammation, Osteoarthritis	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

piroxicam zipsor

Rating

72/100

New

Pharmacy pays

~$5.35 /30

$0.36 /mL

Type

Active ingredient

PIROXICAM

DICLOFENAC POTASSIUM

Manufacturer

Unichem

Assertio Speclty

Dosage forms

Capsule

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

—

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

Treats

Rheumatoid Arthritis, Inflammation, Osteoarthritis

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Frequently asked questions

What is the difference between Piroxicam and Zipsor?

Piroxicam contains Piroxicam, while Zipsor contains Diclofenac Potassium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.