PIROXICAM vs RELAFEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. PIROXICAM and RELAFEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PIROXICAM	RELAFEN
Rating	72/100	New
Pharmacy pays	~$5.35 /30	~$4.00 /30
Type	RX	RX
Active ingredient	PIROXICAM	NABUMETONE
Manufacturer	Unichem	Smithkline Beecham
Dosage forms	Capsule	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	None
Treats	Rheumatoid Arthritis, Inflammation, Osteoarthritis	Rheumatoid Arthritis, Inflammation, Osteoarthritis

piroxicam relafen

Rating

72/100

New

Pharmacy pays

~$5.35 /30

~$4.00 /30

Type

Active ingredient

PIROXICAM

NABUMETONE

Manufacturer

Unichem

Smithkline Beecham

Dosage forms

Capsule

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Treats

Rheumatoid Arthritis, Inflammation, Osteoarthritis

Frequently asked questions

Which is cheaper, Piroxicam or Relafen?

Relafen costs pharmacies less to acquire — about $4.00 vs $5.35 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Piroxicam and Relafen?

Piroxicam contains Piroxicam, while Relafen contains Nabumetone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.