PICATO vs ZYCLARA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. PICATO and ZYCLARA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PICATO	ZYCLARA
Rating	70/100	New
Pharmacy pays	—	~$350.38 /30
Type	RX	RX
Active ingredient	INGENOL MEBUTATE	IMIQUIMOD
Manufacturer	Leo Labs	Bausch
Dosage forms	Topical	Topical
Drug class	—	—
Boxed warning	None	None
Treats	Actinic Keratosis	Basal Cell Carcinoma, Condylomata Acuminata, Actinic Keratosis

picato zyclara

Rating

70/100

New

Pharmacy pays

—

~$350.38 /30

Type

Active ingredient

INGENOL MEBUTATE

IMIQUIMOD

Manufacturer

Leo Labs

Bausch

Dosage forms

Topical

Drug class

—

Boxed warning

None

Treats

Actinic Keratosis

Basal Cell Carcinoma, Condylomata Acuminata, Actinic Keratosis

Frequently asked questions

What is the difference between Picato and Zyclara?

Picato contains Ingenol Mebutate, while Zyclara contains Imiquimod — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.