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PHENERGAN vs PROMETHAZINE PLAIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

~$1.53 /30
~$1.53 /30

Type

RX
RX

Active ingredient

PROMETHAZINE HYDROCHLORIDE
PROMETHAZINE HYDROCHLORIDE

Dosage forms

Injectable
Syrup

Drug class

Phenothiazine
Phenothiazine

Half-life

about 9 to 16 hours
about 9 to 16 hours

Treats

Anaphylaxis, Allergic Conjunctivitis, Motion Sickness
Anaphylaxis, Allergic Conjunctivitis, Motion Sickness

Frequently asked questions

Which is cheaper, Phenergan or Promethazine Plain?

Pharmacies pay about the same to acquire either one — roughly $1.53 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Phenergan and Promethazine Plain?

Both Phenergan and Promethazine Plain share the active ingredient Promethazine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.