Skip to content
ppharmaranks
Menu

PERPHENAZINE vs PROLIXIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. PERPHENAZINE and PROLIXIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

68/100
New

Pharmacy pays

~$5.68 /30
~$11.42 /30

Type

RX
RX

Active ingredient

PERPHENAZINE
FLUPHENAZINE HYDROCHLORIDE

Manufacturer

Dosage forms

Tablet
Tablet

Drug class

Phenothiazine
Phenothiazine

Boxed warning

Treats

Tourette Syndrome, Huntington Disease, Nausea
Psychotic Disorders, Schizophrenia

Frequently asked questions

Which is cheaper, Perphenazine or Prolixin?

Perphenazine costs pharmacies less to acquire — about $5.68 vs $11.42 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Perphenazine and Prolixin?

Perphenazine contains Perphenazine, while Prolixin contains Fluphenazine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.