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PEPCID RPD vs TAGAMET HYDROCHLORIDE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. PEPCID RPD and TAGAMET HYDROCHLORIDE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
70/100

Pharmacy pays

~$1.54 /30
~$9.92 /30

Type

RX
RX

Active ingredient

FAMOTIDINE
CIMETIDINE HYDROCHLORIDE

Dosage forms

Tablet, orally disintegrating
Injectable

Drug class

Histamine-2 Receptor Antagonist
Histamine-2 Receptor Antagonist

Boxed warning

None
None

Half-life

2.5 to 3.5 hours

Treats

Duodenal Ulcer, Dyspepsia, Peptic Esophagitis
Duodenal Ulcer, Dyspepsia, Peptic Esophagitis

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Frequently asked questions

Which is better-rated, Pepcid Rpd or Tagamet Hydrochloride in Sodium Chloride 0.9% in Plastic Container?

Pepcid Rpd and Tagamet Hydrochloride in Sodium Chloride 0.9% in Plastic Container are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Pepcid Rpd or Tagamet Hydrochloride in Sodium Chloride 0.9% in Plastic Container?

Pepcid Rpd costs pharmacies less to acquire — about $1.54 vs $9.92 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Pepcid Rpd and Tagamet Hydrochloride in Sodium Chloride 0.9% in Plastic Container?

Pepcid Rpd contains Famotidine, while Tagamet Hydrochloride in Sodium Chloride 0.9% in Plastic Container contains Cimetidine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.