PEPCID PRESERVATIVE FREE vs PEPCID RPD

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	PEPCID PRESERVATIVE FREE	PEPCID RPD
Rating	70/100	70/100
Pharmacy pays	~$1.54 /30	~$1.54 /30
Type	RX	RX
Active ingredient	FAMOTIDINE	FAMOTIDINE
Manufacturer	Merck	Merck
Dosage forms	Injectable	Tablet, orally disintegrating
Drug class	Histamine-2 Receptor Antagonist	Histamine-2 Receptor Antagonist
Boxed warning	None	None
Half-life	2.5 to 3.5 hours	2.5 to 3.5 hours
Treats	Duodenal Ulcer, Dyspepsia, Peptic Esophagitis	Duodenal Ulcer, Dyspepsia, Peptic Esophagitis

pepcid preservative free pepcid rpd

Rating

70/100

Pharmacy pays

~$1.54 /30

Type

Active ingredient

FAMOTIDINE

Manufacturer

Merck

Dosage forms

Injectable

Tablet, orally disintegrating

Drug class

Histamine-2 Receptor Antagonist

Boxed warning

None

Half-life

2.5 to 3.5 hours

Treats

Duodenal Ulcer, Dyspepsia, Peptic Esophagitis

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Frequently asked questions

Which is better-rated, Pepcid Preservative Free or Pepcid Rpd?

Pepcid Preservative Free and Pepcid Rpd are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Pepcid Preservative Free or Pepcid Rpd?

Pharmacies pay about the same to acquire either one — roughly $1.54 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Pepcid Preservative Free and Pepcid Rpd?

Both Pepcid Preservative Free and Pepcid Rpd share the active ingredient Famotidine.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.