PEPCID AC vs ZANTAC 25
Independent side-by-side comparison.
Rating
70/100
New
Pharmacy pays
~$1.54 /30
—
Type
OTC
RX
Active ingredient
FAMOTIDINE
RANITIDINE HYDROCHLORIDE
Manufacturer
Dosage forms
Tablet
Tablet, effervescent
Drug class
Histamine-2 Receptor Antagonist
—
Boxed warning
None
None
Half-life
2.5 to 3.5 hours
about 2.5 to 3 hours
Treats
Duodenal Ulcer, Dyspepsia, Peptic Esophagitis
Duodenal Ulcer, Peptic Esophagitis, Gastroesophageal Reflux
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Where to buy
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Frequently asked questions
What is the difference between Pepcid Ac and Zantac 25?
Pepcid Ac contains Famotidine, while Zantac 25 contains Ranitidine Hydrochloride — they have different active ingredients.
Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.