PEPCID AC vs TAGAMET HB 200

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 14, 2026·How we rate

Attribute	PEPCID AC	TAGAMET HB 200
Rating	70/100	70/100
Pharmacy pays	~$1.54 /30	~$9.92 /30
Type	OTC	RX
Active ingredient	FAMOTIDINE	CIMETIDINE
Manufacturer	Kenvue Brands	Glaxosmithkline
Dosage forms	Tablet	Suspension
Drug class	Histamine-2 Receptor Antagonist	Histamine-2 Receptor Antagonist
Boxed warning	None	None
Half-life	2.5 to 3.5 hours	—
Treats	Duodenal Ulcer, Dyspepsia, Peptic Esophagitis	Duodenal Ulcer, Dyspepsia, Peptic Esophagitis

pepcid ac tagamet hb 200

Rating

70/100

Pharmacy pays

~$1.54 /30

~$9.92 /30

Type

OTC

Active ingredient

FAMOTIDINE

CIMETIDINE

Manufacturer

Kenvue Brands

Glaxosmithkline

Dosage forms

Tablet

Suspension

Drug class

Histamine-2 Receptor Antagonist

Boxed warning

None

Half-life

2.5 to 3.5 hours

—

Treats

Duodenal Ulcer, Dyspepsia, Peptic Esophagitis

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Frequently asked questions

Which is better-rated, Pepcid Ac or Tagamet Hb 200?

Pepcid Ac and Tagamet Hb 200 are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Pepcid Ac or Tagamet Hb 200?

Pepcid Ac costs pharmacies less to acquire — about $1.54 vs $9.92 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Pepcid Ac and Tagamet Hb 200?

Pepcid Ac contains Famotidine, while Tagamet Hb 200 contains Cimetidine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.