FAMOTIDINE vs PEPCID AC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Attribute	FAMOTIDINE	PEPCID AC
Rating	70/100	70/100
Pharmacy pays	~$1.54 /30	~$1.54 /30
Type	RX	OTC
Active ingredient	FAMOTIDINE	FAMOTIDINE
Manufacturer	Micro Labs	Kenvue Brands
Dosage forms	Injectable, Solution, Powder, Tablet	Tablet
Drug class	Histamine-2 Receptor Antagonist	Histamine-2 Receptor Antagonist
Boxed warning	None	None
Half-life	2.5 to 3.5 hours	2.5 to 3.5 hours
Treats	Duodenal Ulcer, Dyspepsia, Peptic Esophagitis	Duodenal Ulcer, Dyspepsia, Peptic Esophagitis

famotidine pepcid ac

Rating

70/100

Pharmacy pays

~$1.54 /30

Type

OTC

Active ingredient

FAMOTIDINE

Manufacturer

Micro Labs

Kenvue Brands

Dosage forms

Injectable, Solution, Powder, Tablet

Tablet

Drug class

Histamine-2 Receptor Antagonist

Boxed warning

None

Half-life

2.5 to 3.5 hours

Treats

Duodenal Ulcer, Dyspepsia, Peptic Esophagitis

Get pepcid ac

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Frequently asked questions

Which is better-rated, Famotidine or Pepcid Ac?

Famotidine and Pepcid Ac are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Famotidine or Pepcid Ac?

Pharmacies pay about the same to acquire either one — roughly $1.54 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Famotidine and Pepcid Ac?

Both Famotidine and Pepcid Ac share the active ingredient Famotidine, but Famotidine is sold as RX and Pepcid Ac as OTC.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.