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PENICILLIN G SODIUM vs POLYCILLIN-N

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. PENICILLIN G SODIUM and POLYCILLIN-N are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
New

Pharmacy pays

~$13.42 /30

Type

RX
RX

Active ingredient

PENICILLIN G SODIUM
AMPICILLIN SODIUM

Dosage forms

Injectable
Injectable

Drug class

Penicillin-Class Antibacterial
Penicillin-Class Antibacterial

Boxed warning

None
None

Treats

Actinomycosis, Anthrax, Botulism
Actinomycosis, Human Bites, Bacillary Dysentery

Frequently asked questions

What is the difference between Penicillin G Sodium and Polycillin-N?

Penicillin G Sodium contains Penicillin G Sodium, while Polycillin-N contains Ampicillin Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.