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PAROXETINE HYDROCHLORIDE vs PAXIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Rating

66/100
66/100

Pharmacy pays

~$2.84 /30
~$2.84 /30

Type

RX
RX

Active ingredient

PAROXETINE HYDROCHLORIDE
PAROXETINE HYDROCHLORIDE

Manufacturer

Dosage forms

Suspension, Tablet, extended release
Tablet

Drug class

Serotonin Reuptake Inhibitor
Serotonin Reuptake Inhibitor

Boxed warning

Half-life

about 21 hours on average (the label reports a mean of approximately 21 hours, with 32% variability between people)
about 21 hours on average (the label reports a mean of approximately 21 hours, with 32% variability between people)

Treats

Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder
Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder

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Frequently asked questions

Which is better-rated, Paroxetine Hydrochloride or Paxil?

Paroxetine Hydrochloride and Paxil are tied at 3.3 out of 5 by our independent rating.

Which is cheaper, Paroxetine Hydrochloride or Paxil?

Pharmacies pay about the same to acquire either one — roughly $2.84 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Paroxetine Hydrochloride and Paxil?

Both Paroxetine Hydrochloride and Paxil share the active ingredient Paroxetine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.