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PATHOCIL vs PENBRITIN-S

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. PATHOCIL and PENBRITIN-S are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
New

Pharmacy pays

~$23.69 /30
~$13.42 /30

Type

RX
RX

Active ingredient

DICLOXACILLIN SODIUM
AMPICILLIN SODIUM

Dosage forms

Capsule
Injectable

Drug class

Penicillin-Class Antibacterial
Penicillin-Class Antibacterial

Boxed warning

None
None

Treats

Cellulitis, Osteomyelitis, Postoperative Complications
Actinomycosis, Human Bites, Bacillary Dysentery

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Frequently asked questions

Which is cheaper, Pathocil or Penbritin-S?

Penbritin-S costs pharmacies less to acquire — about $13.42 vs $23.69 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Pathocil and Penbritin-S?

Pathocil contains Dicloxacillin Sodium, while Penbritin-S contains Ampicillin Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.