PATADAY ONCE DAILY RELIEF vs ZYRTEC HIVES

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Attribute	PATADAY ONCE DAILY RELIEF	ZYRTEC HIVES
Rating	New	70/100
Pharmacy pays	$1.23 /g	$0.06 /mL
Type	OTC	RX
Active ingredient	OLOPATADINE HYDROCHLORIDE	CETIRIZINE HYDROCHLORIDE
Manufacturer	Alcon	Kenvue Brands
Dosage forms	Solution	Solution
Drug class	Histamine-1 Receptor Antagonist	Histamine-1 Receptor Antagonist
Boxed warning	None	None
Half-life	—	about 8.3 hours (mean in healthy adults)
Treats	Allergic Conjunctivitis	Perennial Allergic Rhinitis, Urticaria

pataday once daily relief zyrtec hives

Rating

New

70/100

Pharmacy pays

$1.23 /g

$0.06 /mL

Type

OTC

Active ingredient

OLOPATADINE HYDROCHLORIDE

CETIRIZINE HYDROCHLORIDE

Manufacturer

Alcon

Kenvue Brands

Dosage forms

Solution

Drug class

Histamine-1 Receptor Antagonist

Boxed warning

None

Half-life

—

about 8.3 hours (mean in healthy adults)

Treats

Allergic Conjunctivitis

Perennial Allergic Rhinitis, Urticaria

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Frequently asked questions

What is the difference between Pataday Once Daily Relief and Zyrtec Hives?

Pataday Once Daily Relief contains Olopatadine Hydrochloride, while Zyrtec Hives contains Cetirizine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.