PAROXETINE HYDROCHLORIDE vs PEXEVA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. PAROXETINE HYDROCHLORIDE and PEXEVA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	PAROXETINE HYDROCHLORIDE	PEXEVA
Rating	66/100	New
Pharmacy pays	~$2.84 /30	~$2.84 /30
Type	RX	RX
Active ingredient	PAROXETINE HYDROCHLORIDE	PAROXETINE MESYLATE
Manufacturer	Apotex	Sebela Ireland Ltd
Dosage forms	Suspension, Tablet, extended release	Tablet
Drug class	Serotonin Reuptake Inhibitor	Serotonin Reuptake Inhibitor
Boxed warning	None	None
Half-life	about 21 hours on average (the label reports a mean of approximately 21 hours, with 32% variability between people)	about 21 hours on average (the label reports a mean of approximately 21 hours, with 32% variability between people)
Treats	Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder	Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder

paroxetine hydrochloride pexeva

Rating

66/100

New

Pharmacy pays

~$2.84 /30

Type

Active ingredient

PAROXETINE HYDROCHLORIDE

PAROXETINE MESYLATE

Manufacturer

Apotex

Sebela Ireland Ltd

Dosage forms

Suspension, Tablet, extended release

Tablet

Drug class

Serotonin Reuptake Inhibitor

Boxed warning

None

Half-life

about 21 hours on average (the label reports a mean of approximately 21 hours, with 32% variability between people)

Treats

Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder

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Frequently asked questions

Which is cheaper, Paroxetine Hydrochloride or Pexeva?

Pharmacies pay about the same to acquire either one — roughly $2.84 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Paroxetine Hydrochloride and Pexeva?

Paroxetine Hydrochloride contains Paroxetine Hydrochloride, while Pexeva contains Paroxetine Mesylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.