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OXYCODONE HYDROCHLORIDE vs XTAMPZA ER

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. OXYCODONE HYDROCHLORIDE and XTAMPZA ER are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

$0.08 /mL
$0.08 /mL

Type

RX
RX

Active ingredient

OXYCODONE HYDROCHLORIDE
OXYCODONE

Dosage forms

Solution, Tablet, Tablet, extended release
Capsule, extended release

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

Half-life

about 3.5 to 4 hours
about 3.5 to 4 hours

Treats

Postoperative Pain
Postoperative Pain

Frequently asked questions

Which is cheaper, Oxycodone Hydrochloride or Xtampza ER?

Pharmacies pay about the same to acquire either one — roughly $0.08 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Oxycodone Hydrochloride and Xtampza ER?

Oxycodone Hydrochloride contains Oxycodone Hydrochloride, while Xtampza ER contains Oxycodone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.