ORTHO CYCLEN-21 vs TRI-LO-ESTARYLLA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Attribute	ORTHO CYCLEN-21	TRI-LO-ESTARYLLA
Rating	70/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	ETHINYL ESTRADIOL AND NORGESTIMATE	ETHINYL ESTRADIOL AND NORGESTIMATE
Manufacturer	Janssen Pharms	Xiromed
Dosage forms	Tablet	Kit
Drug class	—	—
Boxed warning	None	Boxed warning

ortho cyclen-21 tri-lo-estarylla

Rating

70/100

New

Pharmacy pays

—

Type

Active ingredient

ETHINYL ESTRADIOL AND NORGESTIMATE

Manufacturer

Janssen Pharms

Xiromed

Dosage forms

Tablet

Kit

Drug class

—

Boxed warning

None

Boxed warning

Frequently asked questions

What is the difference between Ortho Cyclen-21 and Tri-Lo-Estarylla?

Both Ortho Cyclen-21 and Tri-Lo-Estarylla share the active ingredient Ethinyl Estradiol and Norgestimate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.