ORLAAM vs VIVITROL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. ORLAAM and VIVITROL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ORLAAM	VIVITROL
Rating	New	70/100
Pharmacy pays	—	~$36.35 /30
Type	RX	RX
Active ingredient	LEVOMETHADYL ACETATE HYDROCHLORIDE	NALTREXONE
Manufacturer	Roxane	Alkermes Inc
Dosage forms	—	Kit
Drug class	—	Opioid Antagonist
Boxed warning	None	None
Treats	Opioid-Related Disorders	Alcoholism, Opioid-Related Disorders, Drug Overdose

orlaam vivitrol

Rating

New

70/100

Pharmacy pays

—

~$36.35 /30

Type

Active ingredient

LEVOMETHADYL ACETATE HYDROCHLORIDE

NALTREXONE

Manufacturer

Roxane

Alkermes Inc

Dosage forms

—

Kit

Drug class

—

Opioid Antagonist

Boxed warning

None

Treats

Opioid-Related Disorders

Alcoholism, Opioid-Related Disorders, Drug Overdose

Frequently asked questions

What is the difference between Orlaam and Vivitrol?

Orlaam contains Levomethadyl Acetate Hydrochloride, while Vivitrol contains Naltrexone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.