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ORAMORPH SR vs ROXICODONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. ORAMORPH SR and ROXICODONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

$2.61 /mL
$0.08 /mL

Type

RX
RX

Active ingredient

MORPHINE SULFATE
OXYCODONE HYDROCHLORIDE

Dosage forms

Tablet, extended release
Tablet

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

None
None

Half-life

about 2 hours
about 3.5 to 4 hours

Treats

Dyspnea, Intractable Pain
Postoperative Pain

Frequently asked questions

Which is cheaper, Oramorph SR or Roxicodone?

Roxicodone costs pharmacies less to acquire — about $0.08 vs $2.61 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Oramorph SR and Roxicodone?

Oramorph SR contains Morphine Sulfate, while Roxicodone contains Oxycodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.