OPDIVO vs RYLAZE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. OPDIVO and RYLAZE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	OPDIVO	RYLAZE
Rating	72/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	NIVOLUMAB	ASPARAGINASE ERWINIA CHRYSANTHEMI (RECOMBINANT)-RYWN
Manufacturer	Bristol Myers Squibb	Jazz
Dosage forms	Injectable	Injectable
Drug class	Programmed Death Receptor-1 Blocking Antibody	—
Boxed warning	None	None
Treats	Urinary Bladder Neoplasms, Non-Small-Cell Lung Carcinoma, Squamous Cell Carcinoma	Cholelithiasis, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

opdivo rylaze

Rating

72/100

New

Pharmacy pays

—

Type

Active ingredient

NIVOLUMAB

ASPARAGINASE ERWINIA CHRYSANTHEMI (RECOMBINANT)-RYWN

Manufacturer

Bristol Myers Squibb

Jazz

Dosage forms

Injectable

Drug class

Programmed Death Receptor-1 Blocking Antibody

—

Boxed warning

None

Treats

Urinary Bladder Neoplasms, Non-Small-Cell Lung Carcinoma, Squamous Cell Carcinoma

Cholelithiasis, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

Frequently asked questions

What is the difference between Opdivo and Rylaze?

Opdivo contains Nivolumab, while Rylaze contains Asparaginase Erwinia Chrysanthemi (Recombinant)-Rywn — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.