OPANA vs SUFENTA PRESERVATIVE FREE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. OPANA and SUFENTA PRESERVATIVE FREE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	OPANA	SUFENTA PRESERVATIVE FREE
Rating	72/100	72/100
Pharmacy pays	~$36.74 /30	—
Type	RX	RX
Active ingredient	OXYMORPHONE HYDROCHLORIDE	SUFENTANIL CITRATE
Manufacturer	Endo Pharms	Rising
Dosage forms	Tablet, Injectable	Injectable
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	None
Treats	Pain	Pain

opana sufenta preservative free

Rating

72/100

Pharmacy pays

~$36.74 /30

—

Type

Active ingredient

OXYMORPHONE HYDROCHLORIDE

SUFENTANIL CITRATE

Manufacturer

Endo Pharms

Rising

Dosage forms

Tablet, Injectable

Injectable

Drug class

Opioid Agonist

Boxed warning

None

Treats

Pain

Frequently asked questions

Which is better-rated, Opana or Sufenta Preservative Free?

Opana and Sufenta Preservative Free are tied at 3.6 out of 5 by our independent rating.

What is the difference between Opana and Sufenta Preservative Free?

Opana contains Oxymorphone Hydrochloride, while Sufenta Preservative Free contains Sufentanil Citrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.