ONUREG vs TOLAK

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. ONUREG and TOLAK are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ONUREG	TOLAK
Rating	New	72/100
Pharmacy pays	—	$0.61 /mL
Type	RX	RX
Active ingredient	AZACITIDINE	FLUOROURACIL
Manufacturer	Bristol	Hill Dermaceuticals
Dosage forms	Tablet	Topical
Drug class	Nucleoside Metabolic Inhibitor	Nucleoside Metabolic Inhibitor
Boxed warning	None	None
Treats	Refractory Anemia, Sideroblastic Anemia, Chronic Myelomonocytic Leukemia	Breast Neoplasms, Basal Cell Carcinoma, Colonic Neoplasms

onureg tolak

Rating

New

72/100

Pharmacy pays

—

$0.61 /mL

Type

Active ingredient

AZACITIDINE

FLUOROURACIL

Manufacturer

Bristol

Hill Dermaceuticals

Dosage forms

Tablet

Topical

Drug class

Nucleoside Metabolic Inhibitor

Boxed warning

None

Treats

Refractory Anemia, Sideroblastic Anemia, Chronic Myelomonocytic Leukemia

Breast Neoplasms, Basal Cell Carcinoma, Colonic Neoplasms

Frequently asked questions

What is the difference between Onureg and Tolak?

Onureg contains Azacitidine, while Tolak contains Fluorouracil — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.