ONA-MAST vs TENUATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ONA-MAST and TENUATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ONA-MAST	TENUATE
Rating	New	New
Pharmacy pays	~$2.54 /30	~$7.96 /30
Type	RX	RX
Active ingredient	PHENTERMINE HYDROCHLORIDE	DIETHYLPROPION HYDROCHLORIDE
Manufacturer	Mast Mm	Mpp Pharma
Dosage forms	Capsule, Tablet	Tablet, Tablet, extended release
Drug class	Sympathomimetic Amine Anorectic	Sympathomimetic Amine Anorectic
Boxed warning	None	None
Treats	Obesity	Obesity

ona-mast tenuate

Rating

New

Pharmacy pays

~$2.54 /30

~$7.96 /30

Type

Active ingredient

PHENTERMINE HYDROCHLORIDE

DIETHYLPROPION HYDROCHLORIDE

Manufacturer

Mast Mm

Mpp Pharma

Dosage forms

Capsule, Tablet

Tablet, Tablet, extended release

Drug class

Sympathomimetic Amine Anorectic

Boxed warning

None

Treats

Obesity

Frequently asked questions

Which is cheaper, Ona-Mast or Tenuate?

Ona-Mast costs pharmacies less to acquire — about $2.54 vs $7.96 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Ona-Mast and Tenuate?

Ona-Mast contains Phentermine Hydrochloride, while Tenuate contains Diethylpropion Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.