OMNIPAQUE 12 vs OPTIRAY 300

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. OMNIPAQUE 12 and OPTIRAY 300 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	OMNIPAQUE 12	OPTIRAY 300
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	IOHEXOL	IOVERSOL
Manufacturer	Ge Healthcare	Liebel-Flarsheim
Dosage forms	Injectable, Solution	Injectable
Drug class	Radiographic Contrast Agent	Radiographic Contrast Agent
Boxed warning	Boxed warning	Boxed warning

omnipaque 12 optiray 300

Rating

New

Pharmacy pays

—

Type

Active ingredient

IOHEXOL

IOVERSOL

Manufacturer

Ge Healthcare

Liebel-Flarsheim

Dosage forms

Injectable, Solution

Injectable

Drug class

Radiographic Contrast Agent

Boxed warning

Frequently asked questions

What is the difference between Omnipaque 12 and Optiray 300?

Omnipaque 12 contains Iohexol, while Optiray 300 contains Ioversol — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.