OMEPRAZOLE vs OMEPRAZOLE MAGNESIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. OMEPRAZOLE and OMEPRAZOLE MAGNESIUM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	OMEPRAZOLE	OMEPRAZOLE MAGNESIUM
Rating	New	68/100
Pharmacy pays	~$1.52 /30	—
Type	RX	RX
Active ingredient	OMEPRAZOLE	OMEPRAZOLE MAGNESIUM
Manufacturer	Hetero Labs Ltd III	Aurobindo Pharma Ltd
Dosage forms	Capsule, Capsule, delayed release, Oral pellets, Tablet, delayed release, Tablet, orally disintegrating, delayed release	Capsule, delayed release
Drug class	Proton Pump Inhibitor	Proton Pump Inhibitor
Boxed warning	None	None
Half-life	about 0.5 to 1 hour (roughly half an hour to an hour) in healthy adults	about 0.5 to 1 hour (roughly half an hour to an hour) in healthy adults
Treats	Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux	Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

omeprazole omeprazole magnesium

Rating

New

68/100

Pharmacy pays

~$1.52 /30

—

Type

Active ingredient

OMEPRAZOLE

OMEPRAZOLE MAGNESIUM

Manufacturer

Hetero Labs Ltd III

Aurobindo Pharma Ltd

Dosage forms

Capsule, Capsule, delayed release, Oral pellets, Tablet, delayed release, Tablet, orally disintegrating, delayed release

Capsule, delayed release

Drug class

Proton Pump Inhibitor

Boxed warning

None

Half-life

about 0.5 to 1 hour (roughly half an hour to an hour) in healthy adults

Treats

Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

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Frequently asked questions

What is the difference between Omeprazole and Omeprazole Magnesium?

Omeprazole contains Omeprazole, while Omeprazole Magnesium contains Omeprazole Magnesium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.