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OLOPATADINE HYDROCHLORIDE vs XYZAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. OLOPATADINE HYDROCHLORIDE and XYZAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

66/100
New

Pharmacy pays

$1.23 /g
$0.06 /mL

Type

RX
RX

Active ingredient

OLOPATADINE HYDROCHLORIDE
LEVOCETIRIZINE DIHYDROCHLORIDE

Dosage forms

Solution, Drops, Spray/Inhaler, Spray/Inhaler, metered
Solution, Tablet

Drug class

Histamine-1 Receptor Antagonist
Histamine-1 Receptor Antagonist

Boxed warning

None
None

Treats

Allergic Conjunctivitis
Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Urticaria

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Frequently asked questions

What is the difference between Olopatadine Hydrochloride and Xyzal?

Olopatadine Hydrochloride contains Olopatadine Hydrochloride, while Xyzal contains Levocetirizine Dihydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.