OCREVUS vs PLEGRIDY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. OCREVUS and PLEGRIDY are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	OCREVUS	PLEGRIDY
Rating	70/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	OCRELIZUMAB	PEGINTERFERON BETA-1A
Manufacturer	Genentech Inc	Biogen Idec
Dosage forms	Injectable	Injectable, Kit
Drug class	—	—
Boxed warning	None	None
Treats	Multiple Sclerosis	Multiple Sclerosis

ocrevus plegridy

Rating

70/100

New

Pharmacy pays

—

Type

Active ingredient

OCRELIZUMAB

PEGINTERFERON BETA-1A

Manufacturer

Genentech Inc

Biogen Idec

Dosage forms

Injectable

Injectable, Kit

Drug class

—

Boxed warning

None

Treats

Multiple Sclerosis

Frequently asked questions

What is the difference between Ocrevus and Plegridy?

Ocrevus contains Ocrelizumab, while Plegridy contains Peginterferon Beta-1a — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.