NUZYRA vs XENLETA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. NUZYRA and XENLETA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NUZYRA	XENLETA
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	OMADACYCLINE TOSYLATE	LEFAMULIN ACETATE
Manufacturer	Paratek Pharms	Hong Kong
Dosage forms	Injectable, Tablet	Solution, Tablet
Drug class	—	—
Boxed warning	None	None
Treats	Bacterial Infections, Bacterial Skin Diseases, Bacterial Pneumonia	Bacterial Pneumonia

nuzyra xenleta

Rating

New

Pharmacy pays

—

Type

Active ingredient

OMADACYCLINE TOSYLATE

LEFAMULIN ACETATE

Manufacturer

Paratek Pharms

Hong Kong

Dosage forms

Injectable, Tablet

Solution, Tablet

Drug class

—

Boxed warning

None

Treats

Bacterial Infections, Bacterial Skin Diseases, Bacterial Pneumonia

Bacterial Pneumonia

Frequently asked questions

What is the difference between Nuzyra and Xenleta?

Nuzyra contains Omadacycline Tosylate, while Xenleta contains Lefamulin Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.