NUZYRA vs SIVEXTRO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. NUZYRA and SIVEXTRO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NUZYRA	SIVEXTRO
Rating	New	72/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	OMADACYCLINE TOSYLATE	TEDIZOLID PHOSPHATE
Manufacturer	Paratek Pharms	Cubist Pharms LLC
Dosage forms	Injectable, Tablet	Injectable, Tablet
Drug class	—	—
Boxed warning	None	None
Treats	Bacterial Infections, Bacterial Skin Diseases, Bacterial Pneumonia	Staphylococcal Infections, Streptococcal Infections, Bacterial Skin Diseases

nuzyra sivextro

Rating

New

72/100

Pharmacy pays

—

Type

Active ingredient

OMADACYCLINE TOSYLATE

TEDIZOLID PHOSPHATE

Manufacturer

Paratek Pharms

Cubist Pharms LLC

Dosage forms

Injectable, Tablet

Drug class

—

Boxed warning

None

Treats

Bacterial Infections, Bacterial Skin Diseases, Bacterial Pneumonia

Staphylococcal Infections, Streptococcal Infections, Bacterial Skin Diseases

Frequently asked questions

What is the difference between Nuzyra and Sivextro?

Nuzyra contains Omadacycline Tosylate, while Sivextro contains Tedizolid Phosphate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.