NUVIGIL vs WAKIX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. NUVIGIL and WAKIX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NUVIGIL	WAKIX
Rating	New	New
Pharmacy pays	~$24.34 /30	—
Type	RX	RX
Active ingredient	ARMODAFINIL	PITOLISANT HYDROCHLORIDE
Manufacturer	Nuvo Pharms	Harmony
Dosage forms	Tablet	Tablet
Drug class	—	—
Boxed warning	None	None
Treats	Sleep Wake Disorders	Sleep Wake Disorders

nuvigil wakix

Rating

New

Pharmacy pays

~$24.34 /30

—

Type

Active ingredient

ARMODAFINIL

PITOLISANT HYDROCHLORIDE

Manufacturer

Nuvo Pharms

Harmony

Dosage forms

Tablet

Drug class

—

Boxed warning

None

Treats

Sleep Wake Disorders

Frequently asked questions

What is the difference between Nuvigil and Wakix?

Nuvigil contains Armodafinil, while Wakix contains Pitolisant Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.