NUPLAZID vs ONGENTYS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. NUPLAZID and ONGENTYS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NUPLAZID	ONGENTYS
Rating	New	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PIMAVANSERIN TARTRATE	OPICAPONE
Manufacturer	Acadia Pharms Inc	Amneal
Dosage forms	Capsule, Tablet	Capsule
Drug class	—	—
Boxed warning	Boxed warning	None
Treats	Hallucinations, Parkinson Disease	Parkinson Disease

nuplazid ongentys

Rating

New

70/100

Pharmacy pays

—

Type

Active ingredient

PIMAVANSERIN TARTRATE

OPICAPONE

Manufacturer

Acadia Pharms Inc

Amneal

Dosage forms

Capsule, Tablet

Capsule

Drug class

—

Boxed warning

None

Treats

Hallucinations, Parkinson Disease

Parkinson Disease

Frequently asked questions

What is the difference between Nuplazid and Ongentys?

Nuplazid contains Pimavanserin Tartrate, while Ongentys contains Opicapone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.