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NORTRIPTYLINE HYDROCHLORIDE vs TOFRANIL-PM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. NORTRIPTYLINE HYDROCHLORIDE and TOFRANIL-PM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

68/100
70/100

Pharmacy pays

$0.17 /mL
~$100.18 /30

Type

RX
RX

Active ingredient

NORTRIPTYLINE HYDROCHLORIDE
IMIPRAMINE PAMOATE

Dosage forms

Capsule, Solution
Capsule

Drug class

Tricyclic Antidepressant
Tricyclic Antidepressant

Boxed warning

None
None

Treats

Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Depressive Disorder
Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

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Frequently asked questions

Which is better-rated, Nortriptyline Hydrochloride or Tofranil-Pm?

By our independent rating, Tofranil-Pm scores higher — 3.5 vs 3.4 out of 5 for Nortriptyline Hydrochloride. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Nortriptyline Hydrochloride and Tofranil-Pm?

Nortriptyline Hydrochloride contains Nortriptyline Hydrochloride, while Tofranil-Pm contains Imipramine Pamoate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.